Abstract

EVALUATION OF REPRODUCTIVE HORMONES (LH & FSH) AND IRON PARAMETERS[HEPCIDINE] AMONG WOMEN DIAGNOSED WITH PCOS

J. Lurdhu Mary*, Dr. Kumar Raja Jayavarapu, B. Deekshitha, K. Vikram, R. Nageswari, M. Nandhini, A. Sravani, S. Kavitha, P. Gopal, K. Meghana

Abstract

Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, typically characterized by LH and FSH levels, iron levels, obesity, insulin resistance, and polycystic ovaries. Lifestyle or diet, environmental pollutants, genetics, gut dysbiosis, neuroendocrine alterations, and iron levels are among the risk factors that predispose females to PCOS. These factors might contribute to upsurging metabolic syndrome by causing ferropenia, hepcidine, oxidative stress, hyperandrogenism, impaired folliculogenesis and irregular menstrual cycles. Lifestyle modifications and complementary and alternative medicines are preferred first-line therapy in many cases. Medications, Oral iron supplements (e.g., Ferrous Sulfate, Ferrous Fumarate), Lifestyle modification (weight loss, exercise), Letrozole is often the first-line ovulation induction drug PCOS. This study aims to evaluate iron status in women with PCOS and investigate its association with menstrual irregularities, FSH and LH levels. Assessment of iron status alongside hormonal parameters may provide valuable insights for the management of women with PCOS Iron status with menstrual irregularities.

Keywords: Polycystic ovary syndrome, iron status, LH and FSH levels haematological parameters lifestyle management.