Abstract

FORMULATION AND EVALUATION OF NOVEL HERBAL ANTIAGEING FORMULATION (GEL-CREAM)

Dr. Rashmi Shukla Srivastava* and Khushbu Pravin Shah

Abstract

In the present study, the aim was to formulate a herbal anti-ageing gelcream which overcomes the lacunae of available anti-ageing formulations. The formulated herbal gel-cream contains a mixture of herbal extract (pomegranate extract), nourishing oils (almond oil, olive oil, wheat germ oil , carrot seed oil , grape seed oil and avocado oil ) , volatile oil (orange oil) and gelling agents (Aloe vera and carbomer). Initial studies were carried out on pomegranate extract and orange oil that proved to be efficacious. The herbal gel-cream (F5) which contains pomegranate extract (2%) and orange oil (1%) showed maximum anti-oxidant activity (IC50 value 0.40 mg) and significant anti-bacterial activity in comparison with the marketed synthetic gel (Clindac gel).The pharmaceutical evaluation and stability studies concluded that the scientific approach adapted to formulate herbal gelcream containing combination of herbal extract, volatile oil, nourishing oils and gelling agents is an effective contribution in the segment of anti-ageing formulations.

Keywords: Gel-cream, anti-ageing, anti-oxidants and nourishing oils.