Abstract

IN-VITRO EVALUATION OF HERBS ON HUMAN EPITHELIAL COLON CARCINOMA (CaCo2) AND ITS PERMIABILITY STUDIES

Gopinath S. M*, Shwetha. C.P, Hithysini.K.N and Kaushani Banerjee

Abstract

Cancer is a fatal disease taking many lives across the world and colon cancer stands third among all cancer after lung and breast cancer. Many conventional drugs have been used to treat cancer. Studies have shown that many compounds extracted from plants exhibit anticancer properties and also show negligible side effects. Few plants that have proven to exhibit antioxidant and anticancerous properties according to the literature survey and the phytochemical assays conducted by us, was chosen and tested on human epithelial colon carcinoma (CaCo2 cell lines) in vitro and the drug permeability studies was performed using FACS ( fluorescent Assorted Cell Sorting). In this article we have discussed few related researches and our present work as a review.

Keywords: Colon cancer, Plants, anticancer properties, CaCo2 cell line, permeability studies.