Abstract

BIOCHEMICAL PARAMETERS OF MALE AND FEMALE RATS TREATED WITH CRUDE VENOM OF ECHIS CARINATUS SOCHUREKI SNAKE

Sami J. Al-Maliki, Khalid G. Al-Fartosi*, Baida R. Ali,

Abstract

The present study aimed to investigate the effect of crude venom of Echis carinatus sochureki snake on biochemical parameters of rats. Adult male and female rats divided into three groups for each sex (6 for each group), the first group injected with normal saline (0.9%Nacl) as a control group, the second group injected with (0.04ml/kg/day) of crude venom for once time, and the third group injected with (0.08ml/kg/day) of crude venom for once time. The results indicated the levels of glucose, Creatinine, ALT, AST and HDL were increased significantly in male and female rats , In contrast, the injection of crude venom of the viper Echis carinatus induced a significant decrease in cholesterol, triglycerides, total serum protein, albumin, , ALP, LDL and VLDL in male and female within 24 hr. after injection Viper Echis carinatus crude venom caused hepatic and renal dysfunction in envenomated rats.

Keywords: Echis carinatus sochureki, biochemical parameters, Crude venom, Rats.