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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

SYNTHESIS OF 4-t-BUTYLCALIX [4] ARENES HAVING SUBSTITUTED PHENYL ON METHYLENE BRIDGES

M. M. V. Ramana*, Shrimant V. Rathoda and M. S. Raje

Abstract

The present communication relates to a novel method for preparing 2,8,14,20- tetra (3,4,5,- trimethoxy) phenyl – 5,11,17,23 tetra-tert-butyl 25,26,27,28- tetrahydroxycalix [4] arene (V);2,8,14,20-tetra(2,4,6- trimethoxy)phenyl–5,11,17,23tetra-tert-butyl 25,26,27,28- tetrahydroxycalix [4] arene ( VI):- 2,8,14,20- tetra (4- dimethylamino) phenyl – 5,11,17,23 tetra-tert-butyl 25,26,27,28- tetrahydroxycalix [4] arene ( VII ) in presence of a base.

Keywords: Calix[4]arenes, Macrocycles, Cancer immunotherapy.

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