Abstract

STUDY THE INHIBITORY EFFECTS OF BACILLUS SUBTILIS FILTRATES ISOLATED FROM IRAQI SOIL IN COMBINATION WITH MIC OF CIPROFLOXACIN AND IMIPIMEN ON ACINETOBACTER BAUMANNII ISOLATED FROM WOUNDS AND BURNS

Shahrazad Najem Abdu-Allah* and Amal Husaein Mussa

Abstract

The study were performed to detection the inhibitory effect of filtrates Bacillus subtilis isolated from soil against Acinetobacter baumannii Isolated from wounds and Burns .4 isolates of B. subtilis showed inhibitory activity of filtrate without concentrated and with concentrated against 5isolates of A. baumannii. Antibiotic susceptibility test of A. baumannii was performed and MIC determined to the most effective antibiotic ciprofloxacin and imipimen,and studying the inhibitory effect of the combination the filtrates B. subtilis and sub MIC of these antibiotics against A. baumannii. The result showed that the filtrate of isolate B.subtilis against A .baummani has inhibition effect, when using bacterial filtrate alone, and these activity was increased when using sub MIC of ciprofloxacin and imipimen in combination with filtrates of B. subtilis. Separately. The beast antimicrobial activity was obtained by using Imipenem against A. baummani in combination with filterates.

Keywords: Bacillus subtilis, Acinetobacter baumannii, A. baumannii and B. subtilis.