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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

COMPARATIVE STUDY OF ULTRA LOW DOSE OF INTERMITTENT EPIDURAL BUPIVACAINE WITH BUTORPHANOL VS BUPIVACAINE WITH FENTANYL FOR AMBULATORY LABOUR ANALGESIA.

Dr. Shashiprakash, *Dr. Kalpana Singh, Dr Rk Meena, Dr S Loha, Dr Pratibha, Dr Anil Paswan

Abstract

Introduction- We used epidural butorphanol or fentanyl in combination with bupivacaine to establish their efficacy on labour pain, delivery, maternal satisfaction and neonatal outcome. Method- The study was conducted on 50 full term pregnant women of ASA grade I & II with spontaneous onset of labour who gave consent for lumbar epidural analgesia with catheter technique. The study was undertaken after approval of Institutional Ethical Committee. The parturient were randomly allocated into two groups- Group A & B of 25 each. Group A patients received 0.5 mg(0.5 mL) butorphanol with 11.5 mL of 0.0625% bupivacaine and Group B patients received 25 mcg fentanyl(0.5 mL) with 11.5 mL of 0.0625% bupivacaine(total volume 12 mL in each group). All patients were monitored for progress of labour, duration of analgesia, maternal well being, neonatal outcome, side effects and maternal satisfaction at 15, 30, 60, 90 minutes interval. Result- Pulse rate, SpO2, blood pressure was stable in all patients. Combination of butorphanol with bupivacaine resulted better or equal analgesia than fentanyl with bupivacaine with minimal side effects.

Keywords: Epidural analgesia, bupivacaine, butorphanol, fentanyl, obstetrics.


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