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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ULTRASOUND IRRADIATION ASSISTED SYNTHESIS AND ANTIMICROBIAL SCREENING OF NOVEL CYCLIC Î’-DIKETONES AND ITS TRANSITION METAL COMPLEXES

Nanda S. Korde*, Anjali S. Rajbhoj , Suresh T. Gaikwad, Bhimrao C. Khade

Abstract

1-(5-chloro, 2-hydroxyphenyl)-3-(4-methoxyphenyl) propane-1, 3- dione and its transition metal complexes have been synthesized by ultrasound irradiation method. The diketones are synthesized by using Baker-Venkatraman rearrangement on 5-chloro, 2-acetylphenyl, 4- methoxy benzoate. The synthesized compounds were confirmed by the spectroscopic analysis such as IR, 1H-NMR, 13C-NMR, Mass, Elemental analysis, magnetic susceptibility and were employed for antimicrobial screening.

Keywords: Cyclic ?-diketones, Baker-Venkatraman rearrangement, metal complexes, antimicrobial screening, ultrasound irradiation.

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