Abstract

A CASE REPORT OF EVANS SYNDROME

Dr. Sandeep Ankam, Dr. Vinay Aluri, Dr. Pravallika Guttu*, Neelam Injeti and Dr. Uma
Maheshwara rao

Abstract

Evans syndrome is a rare autoimmune disorder in which the body makes antibodies that destroy the red blood cells, platelets and white blood cells. Patients are diagnosed with thrombocytopenia and Coombs positive haemolytic anaemia and have no other known underlying aetiology. We report a case of autoimmune haemolytic anaemia (AIHA) associated with immune thrombocytopenia which is known as Evans’s syndrome. We conclude, for the early diagnosis of the disease the direct Coomb’s test must be interpreted in conjunction with clinical and other laboratory data to avoid erroneous conclusions, as it can be false-negative. Elution of RBC antibodies is a valid additional procedure to clarify whether auto-antibodies are present in Coomb’s-negative patients.

Keywords: Evans syndrome, Autoimmune haemolytic anaemia (AIHA), Thrombocytopenia, Coomb’s test.