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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
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Abstract

EFFECTS OF DIFFERENT ANTIBIOTICS ADMINISTERED TO INFERTILE MEN WITH LEUKOCYTOSPERMIA ON THE SPERM PARAMETERS

Muhammad-Baqir M-R Fakhrildin, Mohammad Oda Selman* and
Dhamyaa Abed Najim

Abstract

Background: Antibiotics are widely used in the treatment of male infertility, as well as in the different fields of ARTs. However, these antibiotics are related to some harmful effects on sperm parameters. Aim of the study: to find out the effects of antibiotics (Ciprofloxacin. Metronidazole and Levofloxacin) on sperm motility parameters. Materials and methods: Three antibiotics were used involving (ciprofloxacin, metronidazole and levofloxacin (Collectively, sperm grade activity in random ten fields have been counted and the percentages of each grade mean respectively were tallied by using electronic calculator. Result: There are non-significant decrease in the sperm progressive motility and immotility post-treatment as compared with pre-treatment when using ciprofloxacin and metronidazole. There was significant decrease in immotile sperm count and increase in progressive motility, by using levofluxacine as compared with pretreated group. Conclusion: Administration of antibiotics may increase round cells count and increase count of germ cells in leukocytospermic men.

Keywords: Ciprofloxacin, Metronidazole, Levofloxacin, sperm motility, leukocytospermia.


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