Abstract

NANOEMULSION: A NEW SYSTEM FOR DRUG DELIVERY

*Nitin P. Kanwale, Datta Gavali, Dhananjay Patil, Rohit Bhaskar , Abhijit Dhas, Anurag Dwivedi.

Abstract

Nanoemulsions are submicron sized emulsion that is under extensive investigation as drug carriers for improving the delivery of therapeutic agents. These are by far the most advanced nanoparticle systems for the systemic delivery of active pharmaceutical for controlled drug delivery and targeting.These are the thermodynamically stable isotropic system in which two immiscible liquid (water and oil) are mixed to form a single phase by means of an appropriate surfactants or it mixes with a droplet diameter approximately in the range of 0.5-100 um. Nanoemulsion droplet size falls typically in the range of 20-200 nm and shows a narrow size distribution. Nanoemulsion show great promise for the future of cosmetics, diagnostics,drug therapies and biotechnologies. Thus the aim of this review is focused on nanoemulison advantage and disadvantage, various methods of preparation, characterization techniques and the various applications of sub micron size emulsion in different areas such as various route of administration, in chemotherapy, in cosmetic, etc.

Keywords: Nanoemulsion, Submicron size droplet, Self emulsifying agent, Drug delivery system.