Abstract

REVIEW ON OCULAR INSERTS

Pratibha Dwivedi*, Pallavi Chand, G. Gnanarajan and Preety Kotiyal

Abstract

Ocular drug delivery is one of the most challenging and interesting task faced by pharmaceutical researchers .This review is based on the purpose to provide an update on the current knowledge about the field of ocular drug delivery. Major barriers in ocular medication included the ability to maintain the therapeutic level of drug at the site of action for prolonged period of time. That’s why there are many ophthalmic drug delivery system are available which are sterile, buffered & isotonic solution. Eye drop solution is the most prescribed dosage form for the ocular therapy due to its easier and self administration. Ophthalmic preparations must be non irritating to the ocular tissues and homogeneous i.e.: particles must be dispersed uniformly, smooth and free from lumps or agglomerates. It must be relatively non greasy and should not cause blurred vision and also physically and chemically stable. New ocular drug delivery systems are now updated. For the prolongation of drug release the ophthalmic inserts are also used. Ocular inserts are comes under the new drug delivery system. Ocular inserts are described as the preparation which is having solid or semisolid consistency and are especially designed as the size and shape for ophthalmic application (i.e. rods or shields). This system generally includes delayed, controlled and or sustained release.

Keywords: ocular drug delivery system, ocuserts, non erodible ocular insert, bio degradable ophthalmic insert.