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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

SYNTHESIS OF PYRAZOLE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITIES

Sanjay P. Wagh, Vivek R. Tembhare, Chandrakant S. Bhaskar*

Abstract

1-aryl/H-3-methyl-5-(acidhydrazido-N’)-pyrazoles (V) have been synthesized by the interaction of aroyl/acyl-(2-ketobutanoyl)- hydrazines (III) and aryl/H-hydrazines (IV). The structures of all new compounds were confirmed by using elemental and spectral analysis. All the compounds were screened for their antimicrobial activities.

Keywords: pyrazole, acidhydrazido, antimicrobial activities.

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