Abstract

THE COST EFFECTIVE ANALYSIS OF DIFFERENT ANTIBIOTIC USED IN TREATING TYPHOID FEVER IN A TERTIARY CARE CENTRE

*P. Durairajan

Abstract

Objective: To study the cost effective analysis of various antibiotics in the treatment of Typhoid fever in adult population. Methods: In our retrospective study we analyzed 50 case sheets of Typhoid fever patients who were admitted to Sri Muthukumaran Medical College Hospital & Research Institute, Chennai. From January 2014- December 2014 in which various antibiotics given I.V and oral routes were analyzed. We found that commonly Mox, Ceftrixone, Azithrol, Cifran, Chloramphenicol, Trimethoprim+sulfamethoxazole ware used I.V antibiotics showed better improvement than oral antibiotics. So we applied cost – effective analysis of antibiotics and a Pharmacoeconomics evaluation was done. The cost effectiveness coefficient was calculated as the ratio of antibiotics price. Results: The cost effectiveness co-efficient ratio showed continuous i.v. administration of antibiotic is more expensive than the switch over therapy. Conclusion: Timely switch over from I.V antibiotics to oral antibiotics in an appropriate patient is an efficient way to safeguard the undesirable expenses.

Keywords: Amoxicillin, Cifran, Azithromycin.