Abstract

EVALUATION OF MIMOSA PIGRA ROOTS ON HAEMATOLOGICAL AND BIOCHEMICAL PARAMETERS OF ALBINO RATS

Shorinwa Olusayo A.*, Etozuo Nnamdi, Afieroho Ozadheoghene E.

Abstract

To investigate the effect of sub-acute doses of the ethanol extract of mimosa pigra on haematological and biochemical indices in albino rats. Animals of both sexes were divided into four groups of six each. The extract treated groups were administered with oral doses of 250mg/kg, 500mg/kg and 1000mg/kg of the extract while the control received distilled water for 28 days consecutively. Blood samples were collected from the rats on the 29th day for evaluation of haematological (pcv, rbc and hb) and biochemical (ast, alt, alp, total protein, cholesterol, urea, creatinine and total bilirubin) parameters. The results of the study showed that there was a statistically significant (p

Keywords: Mimosa pigra, Sub-acute, Toxicity, Haematological, Biochemical.