Abstract

PHYSICOCHEMICAL AND INSTRUMENTAL STANDARDIZATION OF SIDDHA HERBO MINERAL DRUG KANDHAGA PARPAM

R. Moovendan*, S. Vidhya, N. Saravanan, A. Kingsly, G. EssakkyPandian

Abstract

Kandhaga parpam is one of the traditional Siddha herbo mineral medicine is used in the treatment of diabetes. The aim of this present study was carried out to standardize the drug Kandhaga parpam by evaluating its Organoleptic characters, Physico chemical properties and modern scientific instruments like, Fourier Transform - Infra Red (FTIR) Spectroscopy, SEM (Scanning Electron Microscope). Organoleptic characters such as colour, odour, particle size and Physico-Chemical Characters like ash Values, pH value were analyzed. The total ash value was found to be 26.96%w/w, acid insoluble ash value is 9.05%w/w and moisture content is 3.59% w/w. The pH value is 9.4. FT-IR spectroscopy showed the presence of functional groups like amines, aliphatic amines, primary amines, amides and alkyl halides. These functional groups are key factors for anti diabetic activity. SEM analysis of the drug indicated the existence of nano particles. Nano particle sizes are 12.4 nm, 27.7 nm, 35.1 nm and 39.2 nm.

Keywords: Physico-chemical properties, ash values, FT-IR spectroscopy, SEM.