Abstract

ISOLATION, PURIFICATION AND CHARACTERIZATION OF ERYTHRINA INDICA AND TESTING ITS ANTI- CANCER ACTIVITY BY INVITRO STUDIES

T. Karthick*, B. Guru Jeya, R. Vimal Raj, B. Sumithra, K. P. Bhuvaneshwari, J. JayaBarath

Abstract

Erythrina indica (Fabaceae) is one of the important medicinal plants coasts of India and Malaysia. Some of its medicinal usage has been mentioned in traditional system of medicine such as Ayurveda, siddha and unani. Seeds of Erythrina used in folk remedies for cancer, whose bark is used for fever, hepatitis, malaria, rheumatism, toothache also for boils and fractures. Now there is a growing importance for the anticancer drug, which reveals the new study of traditionally used medicinal plants. New researches were developing to produce anticancer drug, having no side effects. Objective: This study aims at analysing the anti-cancer activity of Erythrina indica, using rat cell lines. Methods: the DPPH Scavenging activity and Anti- Lipid Per oxidation activities are used to study the Anti-cancer activity. Results: The colour change showed that the presence of Anti-cancer activity in Erithrina indica plant and the Anti lipid peroxidation activity showed that Erithrina indica has potent anti-cancer activity. Conclusion: The study proved that Erithrina indica plant has moderate to potent anti -cancer activity.

Keywords: Erythrina indica, anti- cancer activity, DPPH method and Anti Lipid Per oxidation activity.