Abstract

CLINICAL STUDY ON THE EFFICACY AND SAFETY OF TRYUSHNADI GUGGULU IN MEDOROGA WITH SPECIAL REFERENCE TO DYSLIPIDEMIA

*Dr. Anchal Bilyan, Dr. Udai Raj Saroj and Dr. Ajay Kumar Sah

Abstract

Dyslipidaemia is a disorder of lipoprotein metabolism, which can include overproduction or deficiency of lipoproteins or both. The disorder can manifest as an elevation of plasma cholesterol, triglycerides, or both, or a low high density lipoprotein level or all three together that contributes to the development of atherosclerosis. The lipids in contemporary science can be correlated with Medas and hence Medohara treatment can be employed in the treatment of hyperlipidaemia (Medo Roga). The study was conducted in P.G. Department of Kaychikitsa, NIA, Jaipur. 45 clinically diagnosed and confirmed patients of Medoroga (Dyslipidaemia) from OPD/IPD of Arogyashala NIA, Jaipur, SSBH, Kishanpole Jaipur. Patients had been administered Trial Drug â€Å¾Tryushnadi Guggulu‟ in dose of 2 Tab. Twice a day (2gm/day) with lukewarm water for 60 days. Assessments were done fortnightly. Duration of study was months. Patients treated with Tryushnadi Guggulu, showed statistically highly significant results (p value <0.0001, <0.001) regarding subjective parameters–Trishna Atinidra, Atikshudha, Alpaprana, whereas in case of Krathana, Kshudrashwasa, Swedadhikya, Daurgandya,, shown significant result ( p value <0.05) In case of objective parameters, in Body weight, Waist-Hip Ratio , Total cholesterol, triglycerides, LDL it has shown highly significant results (p value <0.01). In safety parameters, RFT and LFT it has shown non significant results stastically (p value >0.05).

Keywords: Medoroga, Dyslipideamia, Tryushanadi Guggulu.