Abstract

COMPARITIVE STUDY OF GHRITBHRISHTA HARIDRA & RASAMANIKYA WITH DIETHYL CARBAMAZINE IN VATAJ KASA W. R.T. EOSINOPHILIA

*Dr. Rupali Tarachand Khobragade MD (Kayachikitsa)., Dr. Medha Mahesh Joshi MD (Kayachikitsa), Dr. Pournima Machindra Daware MD (Panchakarma), Dr. Vrinda Hitendra Kurande MD (Kayachikitsa)

Abstract

Background: The prevalence of vatajakasa (dry cough) vis-à-vis Pulmonary Eosinophilia is remarked. High eosinophil count in dry cough often indicates an allergic condition. Conventional medicine for dry cough is symptom based without consistent benefits with side effects like drowsiness and lethargy. Considering the prevalence and long term treatment for allergic dry cough, there is need to investigate drug with better result with no side effect. Aim: To evaluate the anti allergic effect of ghritbhrishta haridra and Rasamanikyain comparison with diethyl carbamazine in cases of Vataj Kasa (Dry cough) – eosinophilia. Materials and Methods: In this study, 60 patients of vatajakasa were randomly divided into two groups (30 in each). In Group A (control)-100mg of Diethyl Carbamazine was administered twice a day. Experimental Group B was given 6 gms Haridra (Curcuma longa linn.) roasted in Ghee combined with Rasamanikya (200 mg) twice a day for 21 days. Findings were recorded at weekly intervals.After treatment, comparison was done using wilcoxins rank test as well as before and after treatment results were calculated using paired and unpaired “t-test”. Results: Significant results (P < 0.05) were found in both groups.Reduction in eosinophil count (P - 0.05), and dry cough (18.96%) was fount in group B as compare with group A (7.75%). Recurrence rate was less in Group B (2.58%) as compare with group A (1.72%) after 3 months. Conclusion: Ghrita Bhrishta Haridra and Rasamanikyamay reduce eosinophil countand also stops recurrence with better symptomatic relief in vatajakasa.

Keywords: Vataj kasa, Eosinophilia, Ghrita Bhrishta Haridra, Rasamanikya, Diethyl carbamazine.