Abstract

ANTIBIOTIC RESISTANCE AND ANTIBIOTIC INDUCED SEIZURE IN A CHRONIC RENAL FAILURE PATIENT

Dr.MD Amer Khan *, Aziz ullah G, M.S Adil, Mohammed Maazuddin, Ihtisham
sultan, Nematullah M.

Abstract

Within the life period, antibiotic resistance has become a major health problem due to increase in the antibiotic utilization over 60 years. Antibiotic resistance occurs before or during the treatment course. Infection is the second leading cause of death in dialysis patients i.e 100 to 300 times more than sepsis. 24% of the infections are related to only dialysis in which Staphylococci organisms are the most common. A 63 old female patient was admitted in the hospital with complaints of fever, burning micturition with decreased urinary output since 1 week, puffiness of face since 2 days and patient was in altered mental state since 2 days, and anorexia. diagnosis made was acute CKD/uremic encephalopathy/septic shock with LRTI/UTI. Ofloxacin induced seizure has been evaluated in this CRF patient and the score found on naranjo scale is 6 i.e probable. The renal failure patient should be carefully monitored with anitbiotics and doasage adjustment should be done if possible.

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