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World Journal of Pharmaceutical Research

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An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

IN-VITRO ANTIOXIDANT AND ANTINEOPLASTIC ACTIVITIES OF CAROTENOIDS FROM FLOWERS OF KOELREUTERIA PANICULATA

Iliya Zhelev?, Kaloyan Georgiev, Ivanka Dimitrova-Dyulgerova

Abstract

Isolation and quantification by HPLC analysis of carotenoid fraction from flowers of Koelreuteria paniculata were done for the first time. β-carotene (2899.95μg/g extract) were the compound with the highest concentration, followed by lycopene (569.87 μg/g extract) and lutein (538.34 μg/g extract). The tested extract showed a good in-vitro antioxidant activity by ABTS method (368.86±39.58 mMTE/g extract), whereas antineoplastic potential was week on all tested cell lines.

Keywords: Koelreuteria paniculata, flowers, carotenoids, HPLC, antioxidant activity, antineoplastic activity.

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