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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

IONIC LIQUIDS â€“CATALYZED A GREEN SYNTHESIS OF 3, 4- DIHYDROPYRIMIDIN- 2 (1H) - ONES UNDER SOLVENT- FREE CONDITIONS

Rehana Anjum* and Renu Sharma

Abstract

Ionic liquids (ILs) Triethyl ammonium dihydrogen phosphate efficiently catalyzes the condensation reaction of ethyl acetoacetate, aldehydes, and urea or thiourea a three-component reaction under solvent-free conditions. The reaction proceeds rapidly and affords the corresponding 3, 4-dihydropyrimidin-2 (1H)-ones in high yields, short reaction times, simple procedure.

Keywords: Ionic liquids, Triethyl ammonium dihydrogen phosphate [Et3NH] [H2PO4], 3, 4-dihydropyrimidin-2 (1H)-ones, solvent- free.

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