Abstract

ANTIMICROBIAL ACTIVITY OF MORINGA OLEIFERA (MORINGACEAE) AND BARLERIA PRIONITIS (ACANTHACEAE) METHANOLIC CRUDE LEAVES EXTRACT

Padma Shrivastava* and Priyam Singh

Abstract

The nature provides the mankind vast therapeutic flora with a wide variety of medicinal potential. According to WHO world’s 80% population depends on traditional medicines for healthcare. Phytochemical screening show the presence of saponin, flavonoids, carbohydrate, glycosides, terpenes and steroids in Moringa oleifera methanolic crude leaves extract. Phytochemical screening of Barleria prionitis showed the presence of terpenes, glycosides and flavonoids. Both the plants showed the anti microbial activity in the dose dependent manner. M. oleifera mehanolic crude leaf extract showed antimicrobial activity against Pseudomonas aeruginosa with zone of inhibition of 6.0 ± 0.05, 10.0 ± 0.02, 11.0 ± 0.01, 14.0 ± 0.033 mm in concentration of 25,50,75,100 % respectively of crude extract as compare to Streptomycin 9.9 ± 0.47 with concentration of 10μg/disc. B. prionitis methanolic crude extract showed antimicrobial activity against Streptococcus mutans with zone of inhibition of 6.0 ± 0.05, 10.0 ± 0.02, 6.0 ± 0.01, 7.0 ± 0.033 mm in concentration of 25,50,75,100 % respectively of crude extract as compare to Streptomycin 9.9 ± 0.47 with concentration of 10μg/disc.

Keywords: antimicrobial, medicinal potential, flavonoids, saponin, steroids, terpenes.