Abstract

SYNTHESIS OF SOME NOVEL THIAZOLIDINE DERIVATIVES WITH BENZOTHIAZOLE MOIETY.

Nilesh Mohan Gosavi*

Abstract

As a part of systematic investigation of synthesis of N-[2-(2- chloroquinolin-3-yl)-4-oxo-1, 3-thiazolidin-3-yl]-1, 3-benzothiazole-2- carboxamide V (a-g) was achieved by corresponding manich bases IV (a-g) by reaction with thioglycolic acid. Manich base IV (a-g) was prepared by corresponding quinolene derivative III (a-g) and 1, 3- benzothiazole-2-carbohydrazide II. The synthesized compounds have been characterized by physico-chemical and spectral analysis.

Keywords: Thiazolidine, Benzothiazole, Mannich bases, Zeolite.