WJPR
World Journal of Pharmaceutical Research
( An ISO 9001:2015 Certified International Journal )
An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
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WJPR Citation
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| All | Since 2020 | |
| Citation | 8502 | 4519 |
| h-index | 30 | 23 |
| i10-index | 227 | 96 |
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Best Paper Award : Dr. Dhrubo Jyoti Sen
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Abstract
SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION FOR AMLODIPINE BESYLATE AND SIMVASTATIN IN BULK AND TABLET DOSAGE FORM USING ABSORPTION RATIO METHODSathis Kumar Dinakaran*, Koyya SivaKumar, Anusha Pothula, Avasarala Harani
Abstract A simple, economic and accurate absorption ratio method was developed for the simultaneous estimation of Amlodipine besylate and Simvastatin in bulk and tablet dosage form. 0.1M HCL in 1% Sodim Lauryl Sulphate was used as a diluent. The absorptions were observed at 249.78nm and 367.85nm which were selected based on overlap spectra of Amlodipine besylate and Simvastatin. The Linearity range was found to be 5-30ug/ml (r2 =0.999) at 249.78nm and (r2 = 0.996) at 367.85nm. The proposed method was validated. The reports was expressed that the proposed method was found to be simple, precise, accurate and rapid for the simultaneous estimation of Amlodipine besylate and Simvastatin in bulk and tablet dosage form using absorption ratio method. Keywords: [Full Text Article] [Download Certificate] |
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