Abstract

DETERMINATION OF HERBAL PRODUCT CARDIOL VATI BY ICPMS VALIDATION AND APPLICATION

Raju P. Suryawanshi* and Sudhir S. Kamat

Abstract

Popularity of herbal medicines is growing worldwide because of their minimal side effects. Herbal medicines required standardization, with implementation and constant review of technical standards of production and effective quality control methods. It is necessary to promote this study in the view of the importance of results of both individual and social field. Ayurveda names three elemental substances, called Vata, Pitta and Kapha, and states that a balance results in health, while imbalance results in disease. Plant-based treatments in Ayurveda derived from roots, leaves, fruits, bark, seeds. The origins of Ayurveda have been traced back to around 5,000 BC. Fe (Iron) is an important and essential element in human being and plays a vital role in the formation of hemoglobin, oxygen and electron transfer in human body. Cu and Cd also having importance for human being as an essential trace elements. In human, these metal can cause severe physiological and health effects. Hence in present study, herbal medicine samples of Cardiol vati is scanned for the validation and application. Herbal medicines contain many Toxic, Essential, Trace metals. Minerals, Alkaloids, Steroids and organic compounds, besides that it also contain enzymes, proteins, alkaloids. For the present study Cardiol Vati was scanned and detect the heavy metals like Cd (Cadmium), Fe (Iron), Cu (Copper) etc. was scanned and these metals are evaluated and validated quantitatively and statistically by using ICP-MS, which can be incorporated in routine quality control parameters.

Keywords: ICP-MS, herbal tablets, Cardiol Vati, elemental analysis, validation, Herbal quality controlled.