Abstract

EVALUATION OF SERUM ALBUMIN AND OTHER BIOCHEMICAL PARAMETERS IN PATIENTS WITH CHRONIC PERIODONTITIS

Dr. Reshama Y. Sawant* and Dr. Chitra Y. Dhume

Abstract

Chronic periodontitis is an inflammatory disease of the oral cavity resulting in inflammation within the supporting tissue of the teeth with progressive clinical attachment and bone loss. It is most prevalent form of periodontitis. It is observed that in presence of systemic disease like DM etc which influences the host defense mechanism the progression of the disease is more aggressive. This study was undertaken to evaluate serum albumin levels which is a practical marker of general health status. Since albumin is synthesised in the liver, presence of any liver abnormality is also detected by measuring the serum level of enzymes like alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP). It has been suggested that liver abnormality could make individual more susceptible to periodontal disease. The present study included 80 subjects, 40 were chronic periodontitis patients and 40 were healthy subjects. The subjects in the study and control group were aged between 30 to 60 years. The biochemical parameters which were evaluated were serum albumin, serum al alanine transaminase, aspartate transaminase and alkaline phosphatase. It was found that serum albumin levels were significantly lower in chronic periodontitis patients than healthy subjects. Inverse association was seen between serum albumin and clinical attachment loss in chronic periodontitis patients. Serum ALT and ALP showed significant increase in patients with chronic periodontitis as compared to healthy subjects. This study was undertaken to evaluate the role of serum albumin and liver enzymes in the cause effect relationship of chronic periodontitis.

Keywords: Chronic periodontitis, Serum albumin, Alanine transaminase, Alkaline Phosphatase.