Abstract

LIMITED JOINT MOBILITY IN PATIENTS WITH TYPE 1 DIABETES MELLITUS

*Dr. R. H. Lakshmi, MD and Dr. J. V. Balasubramaniyan, MD.

Abstract

Life expectancy of those developing Type 1 Diabetes Mellitus under the age of 20 years is reduced by 30% and 50% of all such patients will no longer be alive after 30 years of Type 1 Diabetes.[1] Many, if not all, of the long term complications of Diabetes such as nephropathy, retinopathy as well as the macrovascular complications that contribute to the increased mortality and morbidity in these patients are considered related to ambient and chronic elevation of blood glucose levels. Prevailing evidence suggests that glycosylation of tissue proteins associated with chronic hyperglycaemia may be responsible for many of these complications.[2]

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