Abstract

PHENYTOIN INDUCED GINGIVAL HYPERTROPHY AND HIRSUTISM

Babitha Annie Eapen*, Ammu A., Chaithra S., S. Hemalatha and T. Sivakumar

Abstract

Phenytoin is commonly used antiepileptic agent, mainly to treat generalized convulsion and partial seizure. The serious side effect of phenytoin ranges from therapeutic dose to toxic dose. We present a case of 35 year old female patient on phenytoin therapy for past 1 year for seizure and presented with complaints of gingival hypertrophy with bleeding gum, maloccluded teeth and hirsutism. Based on the clinical examination, her condition was diagnosed as phenytoin induced multiple adverse drug reaction. The clinical symptoms improved on withdrawing the offending agent and were started with sodium valproate.

Keywords: Antiepileptic agent, phenytoin, gingival hyperplasia, hirsutism.