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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

A CONVENIENT ONE-POT SYNTHESIS OF TETRAHYDROBENZO- [C]-XANTHENE-1,11-DIONE DERIVATIVES IN AQUEOUS MEDIUM

Avinash V. Chakrawar, Shrikant S. Pendalwar, Nagesh D. Mandode,
Sudhakar R. Bhusare*

Abstract

A simple and efficient one-pot synthesis of xanthene derivatives was achieved in excellent yield via the three-component reaction of aromatic aldehydes, 4-hydroxyl coumarin and 5,5- dimethylcyclohexane-1,3-dione using pyrrolidine based organocatalyst in solvent water.

Keywords: One-pot synthesis, Organocatalyst, Tetrahydrobenzo[C]Xanthene-1,11-dione, 4-Hydroxyl coumarin, 5,5- Dimethylcyclohexane-1,3-dione.

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