Abstract

PHARMACOGNOSTICAL AND PHYSICO - CHEMICAL EVALUATION OF SHARAPUNKHADI YOGA - A PROMISING HERBAL FORMULATION FOR NON ALCOHOLIC FATTY LIVER DISEASE

Remya E.*, Mandip Goyal, C. R. Harisha and V. J. Shukla

Abstract

Sharapunkhadi Yoga is a formulated combination comprising of equal quantities of extracts of Sharapunkha, Bhoomiamalaki and Katuki. Each single drug of this formulation is proven to have significant hepatoprotective activity as per Ayurvedic classics and modern pharmacological experiments in animal models. Non Alcoholic Fatty Liver Disease (NAFLD) is the disease of the era which arises mainly from faulty lifestyle. The clinical implications of NAFLD are derived mostly from its common occurrence in the general population, as well as its potential to progress to cirrhosis and liver failure. Sharapunkhadi Yoga is a promising drug in the management of this dreadful disease. In the present study an attempt has been made to develop pharmacognostical and pharmaceutical standards for extracts of Sharapunkha, Bhoomiamalaki and Katuki and for the formulation itself. Pharmacognostical study revealed presence of starch grains in all the four samples, oleoresins in Katuki and Sharapunkhadi Yoga etc. Physico-chemical studies showed that all the samples are slightly acidic, having pH 6.5 and water soluble extract greater than 90%.

Keywords: Pharmacognosy, Physicochemical analysis, Sharapunkhadi Yoga.