Abstract

ANTIBIOTIC UTILISATION PATTERN IN INDOOR PATIENTS OF MEDICINE DEPARTMENT IN A TERTIARY CARE CENTRE IN EASTERN INDIA

Suhrita Paul*, Tithishri Kundu, Pragnadyuti Mandal*, Manab Nandy and Nidhi Agrahari

Abstract

This is a cross sectional observational study done to evaluate the current antibiotic utilization pattern amongst the in patients of medicine department in a Teaching Hospital in eastern India. 840 prescriptions obtained from inpatients of Medicine Department during the period of 1st June 2015 to 31st August 2015 were included in the study. Data was collected in pre-designed case record form. Baseline parameters, use of antibiotics (single/combination), their dose, duration and route of administration and the different regimes of antibiotics prescribed were noted. Out of 840 Indoor prescriptions reviewed, 400 (47.6%) were with antibiotics. The mean age of the patients was (47.76 ± 18.49) years of which 454 (54.05%) were male. The average number of drugs per prescription was 3.8 (3192 / 840) of which 63.5% (2026/3192) were written in generic name. Average number of antibiotics per prescription with antibiotic was 1.5. Oral antibiotics used were 142 (23.35%) compared to 466(76.64%) injectable antibiotics i.e. in 1:3 ratio. Azithromycin (22.5%) was the most common oral antibiotic followed by rifaximin (18.3%). Ceftriaxone (40.6%) was the most common injectable antibiotic used followed by Piperacillin- tazobactam combination (14.6%). A total of 15 types of parenteral and 11 types of oral antibiotics were prescribed Single antibiotic was prescribed in 264 (64%) cases; whereas combination of 2 and 3 antibiotics were used in 126 (29.5%) and 10 (6.5%) cases respectively.

Keywords: Utilization pattern, antibiotics, medical audit, prescription.