Abstract

STUDY OF FERRITIN IN MALNOURISHED CHILDREN AND ITS CORRELATION WITH HORMONES AND BMI

Pingale Sangeeta Avinash*, Prof. Dr. Patil Vinayak Wamanrao, Dr. Patil Aruna

Abstract

Micronutrient deficiency is the another form of malnutrition. Nearly all deaths linked to micronutrient deficiency are due to a lack of vitamin A, zinc or iron. Present study was designed to assess the efficacy of the study nutritional intervention in terms of ferritin levels before and after the Nutritional Intervention treatment (NIT) and to find correlation of ferritin with growth hormone, cortisol and BMI in malnourished children. This was Open label prospective parallel group active comparator interventional study, 105 Study and 100 control SAM(Severe Acute malnutrition)children of 1 to 5 years of age and either sex were randomly enrolled. Study group was given NIT, providing 2.5 to 3gm Protein and 90-100 kcal/kg body weight/day for three months. Serum ferritin, growth hormone, cortisol levels, height and weight of both groups were estimated before and after the NIT. Before NIT P value for Ferritin, Growth hormone, cortisol and BMI were insignificant and after NIT both were significant. The Correlations of ferritin with cortisol, growth hormone and BMI were noted significant with Pearson correlation coefficient r values 0.207, -0.711 and 0.195 respectively, while poor negative correlations of growth hormone with weight and height have also noted significant with r values -0.196 and -0.243 respectively. The investigators conclude that study nutritional intervention is the effective food supplement for the recovery of impaired ferritin status in SAM children and ferritin has significant correlations with cortisol, growth hormone and BMI.

Keywords: Ferritin, Growth hormone, Cortisol, BMI, Malnutrition, Correlations.