Abstract

DEVELOPMENT OF A POLY HERBAL SOLID DOSAGE FORMULATION USING AMLA WITHANIA AND TULSI EXTRACT IN DIFFERENT RATIO

Parwez Alam*, Dr. Jyoti Gupta and Seema Firdouse

Abstract

The aim of present study was to develop a polyherbal solid dosage formulation using Amla Withania and Tulsi extract in different ratio. Polyherbal formulation was developed by using well documented medicinal plants like Amla fruit, Withania root and Tulsi aerial part. The extracts were prepared by using solvents like 60% ethanol for Amla fruit, 50% ethanol for Withania root and pure ethanol for Tulsi aerial part. After extraction granules were prepared with help of extracts and excipients by using wet granulation technique and granules were evaluated by different methods i.e. Physical appearance of granules, Flow property, Fines, Loss on drying, Bulk density, Tap density, Hausner ratio, Carr's index and Angle of repose. Finally polyherbal tablet was formulated and evaluated by using different methods like Physical appearance of tablets, Thickness of tablets, Weight variation, Hardness, Friability and disintegration.

Keywords: Amla fruits, Withania roots, Tulsi aerial parts, Extract, Formulation, Evaluation.