Abstract

ROLE & FUTURE ASPECTS OF PRIMAQUINE IN MALARIA THERAPY

Pankaj Sharma* and Dr. Mukul Tailang

Abstract

Malaria is major problem in malaria prone zone. This review gives a detail idea about primaquine role and it’s significance in malaria therapy. Nanomedicine drug-delivery systems of primaquine may be developed in the effort to overcome delivery barriers and short half life. Some research articles have shown that primaquine derivatives show better results in comparison to primaquine. In relapsing malaria treatment primaquine 30 mg daily dose is necessary. To overcome this problem transdermal drug delivery system of primaquine may be good choice. Transdermal drug delivery system can minimize side effects like abdominal pain, which produced by orally taken primaquine. In this review, the attention is focused to give a basic idea about primaquine role and its future consideration.

Keywords: Malaria, Primaquine, Prophylaxis, Nanomedicine, Transdermal, Radical Cure.