Abstract

GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GC-MS) ANALYSIS OF PHYTOCOMPONENTS IN THE ROOT, STEM BARK AND LEAF OF VERNONIA AMYGDALINA

Longe Adeteju Olufunmilayo*, Momoh Johnson Oshiobugie and Asoro Iroghama Iyobosa

Abstract

Vernonia amygdalina is a medicinal plant widely used in traditional medicine in Africa and Asia for the treatment of ailments such as diabetes, inflammation, microbial infections and it has hypoglycaemic properties. The chemical constituents of the methanolic extract of Vernonia amygdalina root, stem bark and leaf were investigated using Gas chromatography-mass spectrometry (GC-MS). The GC-MS analysis of the Vernonia amygdalina root, stem bark and leaf extract revealed the existence of the GC-MS chromatogram of twenty six peaks present. Fifteen chemical compounds were identified in the root of V amygdalina, six were found in the stem bark. while five were identified in the leaf of the plant by GC-MS analysis. The result of the analysis showed that Vernonia amygdalina contains important pharmacologically important bioactive compounds. The presence of these bioactive compounds justifies the uses of the plant for various traditional medicines.

Keywords: Bioactive compounds, GC-MS analysis, methanol extract and Vernonia amygdalina