Abstract

REVIEW ON ANTIOXIDANTS ACTIVITY AND ITS EVALUATION

*Rohit Yadav, Saurabh Rajvaidhya, Ajay Samnani

TIT College of Pharmacy, Bhopal, (M.P.) India

Abstract

Oxygen free radical induce damage due to peroxidation to biomembranes and also to DNA, which lead to tissue damage, thus cause occurrence of a number of diseases. There is extensive evidence to involve ROS in the development of degenerative diseases. Antioxidants neutralize the effect of free radicals through different ways and may prevent the body from various diseases. Evidence suggests that Compounds especially from natural sources are capable of providing protection against free radicals. This has attracted a great deal of research interest in natural antioxidants. It is necessary to Screen out medicinal plants for their antioxidant potential. Therefore an attempt has been made to review different in vitro and in vivo models for estimating antioxidant properties of natural products from medicinal plants. All the models are described along with the different standards that can be used for estimation.

Keywords: Antioxidants, DNA, free radicals.