Abstract

PREVENTION OF RADIATION INDUCED HISTOPATHOLOGICAL CHANGES IN ALBINO MICE BY ALOE VERA

Priyanka Dadupanthi*

Abstract

The radio protection by Aloe leaf extract (1000mg/kg b.wt) was studied in liver of Swiss albino mice before radiation exposure (3 Gy gamma-radiation). Mice were autopsied at day 3 post irradiation and liver was taken for histopathological studies. In this study mice, showing distorted hepatic architecture, degranulated and vacouolated cytoplasm in both contol and experimental set. But experimental set mice showed mildly crenated and shrunken nuclei as compare to control. The result of present study suggests that Aloe vera has a radioprotective effect due to their antioxidant and radical scavenging activity.

Keywords: Radiation, Aloe vera, Histopathology, Radioprotection, Albino mice