Abstract

QUALITATIVE PHYTOCHEMICAL ANALYSIS AND PHARMACOLOGICAL ACTION OF SIDDHA FORMULATION SADHAKUPPAI CHOORANAM

R. Savitha*

Abstract

Sadhakuppai Chooranam (SKC) is a polyherbal formulation indicated in Siddha literature for the treatment of Worm infestations in pediatrics. This study was aimed at evaluating the phytochemical and anthelmintic activity of Sadhakuppai Chooranam (SKC). Water extract of two concentration of Sadhakuppai chooranam (90 and 180mg) was tested against the nematode Ascaris lumbricoides and the results were expressed in terms of paralysis and mortality of worms. The drug Piperazine citrate 10mg was used as standard reference drug for this study. The results were statistically analysed by‘t test’. The results showed that the test drug Sadhakuppai Chooranam(180mg) showed early paralysis and mortality of the nematode worms Ascaris lumbricoides when compared to the standard drug Piperazine citrate 10mg. Hence the anthelmintic activity of the Sidha drug Sadhakuppai Chooranam has been demonstrated for the first time.

Keywords: Siddha, Sadhakuppai Chooranam (SKC), Worm infestation, herbal medicine, Anthelmintic activity.