Abstract

DE-ADDICTION POTENTIAL OF CLOVE (EUGENIA CARYOPHYLLATA LINN.) IN OPIATE ADDICTION IN SICKLE CELL DISEASE

Dr. Pallavi Ghadage*, Dr. Sathish H. S, Dr. Niranjan Y. and Dr. N. J. Trivedi

Abstract

Pain due to vaso-occlusive crisis is a universal human experience for sickle cell disease, as it defines the symptom of SCD. Objective measures of the presence and severity are lacking in the pain management which is a challenging task. Acute and chronic pain in SCD shows the pervasive and unfounded fear of drug addiction and drug seeking behaviours. Over 3000 years, magical drugs of opiates have been the main stay of pain relief. Because of relapse of severe pain episodes, patients often get into vicious circle of addiction in SCD, have no choice except resorting to same opiates for pain relief. The excellence of medicinal plants with potent analgesic activity were detailed decades ago, Clove, one such herb which contains volatile oils like Phyto cannabinoids and vanilloids will aide in relieving the pain in SCD. Eugenol interacts with vanilloids receptors in order to produce analgesia. Clove facilitates the de addiction of opiates. Whole clove can be chewed when craving is over powering. Thus, this article tries to emphasis the action of clove in pain management of SCD which may prevent opiate addiction.

Keywords: Clove (Eugenia caryophyllata), De addiction, Sickle cell disease, Opiate addiction.