Abstract

BIOLOGICAL EVALUATION OF ANTHELMINITIC ACTIVITY OF ROOT EXTRACT OF Tephrosia Purpurea IN INDIAN ADULT EARTHWORM

*Sachin S. Thorbole, Harshada A. Gaikwad, Pallavi V. Bhokare, Anand P. Khadke, Anuradha A. Khadke and Tejashwi S. Buwa

Abstract

Tephrosea purpurea is a copiously branched herbaceous perennial plant distributed throughout the tropics which is used in the treatment of diuretics, pimple, tonic, laxative, cough, tumour and bronchitis. The present study is an attempt to explore the Anthelminitic activity of aqueous and methanolic extract of roots of plant Tephrosea purpurea. The various concentrations of aqueous and methanolic extract were evaluated for their Anthelminitic activities on adult Indian earthworms Isenia Foetida. The activities are well compared with the standard drug Piperazine citrate. Methanolic and aqueous extract of roots of Tephrosea purpurea shows significant anthelmintic activity in Indian adult earthworms.

Keywords: Tephrosea purpurea, Anthelminitic activity, Earthworms, Methanolic root extract and aqueous root extract.