Abstract

FORMULATION AND EVALUATION OF IBUPROFEN SUSPENSION USING NATURAL AND SYNTHETIC SUSPENDING AGENTS

V. Naga Lakshmi Ponnada*

Abstract

Ibuprofen is a non steroidal anti-inflammatory drug. It is used to relieve pain from various conditions such as headache, dental pain, menstrual cramps, muscle aches, or arthritis. By using synthetic suspending agents such as methyl cellulose and using natural suspending agents such as fenugreek seed powder, prepare 1%, 2% formulations F1, F2, F3, F4. The method involved in this preparation is trituration method by using mortar and pestle. Evaluation tests are performed such as sedimentation volume, particle size analysis, flow rate, Determination of pH, Determination of viscosity, In-vitro dissolution studies drug, Assay of Ibuprofen. Phytochemical tests and swelling index for fenugreek seed powder, these tests shows that the Ibuprofen suspension F4 shows better stability than other three formulations.

Keywords: Ibuprofen, fenugreek seed powder, methyl cellulose.