Abstract

EFFECTIVENESS OF CARIPILL DRUG IN THE TREATMENT OF DENGUE FEVER

Dr. Abel Abraham Thomas* and Ms. Aksay Kuruvillia

Abstract

Dengue fever is considered to the most common arthropod borne viral illness which is caused by the infestation of Aedes mosquitoes distributed in subtropical and tropical areas of the world. This disease has its most common clinical manifestation of thrombocytopenia leading to severe bleeding and dengue hemorrhagic fever as its major complication. Treatment for dengue is often based on symptoms and many studies have done to done to treat thrombocytopenia. The administration of Carica papaya leaf extract should significantly increase the platelet count in cases of thrombocytopenia associated with dengue, preventing the patient to go in DHF or DSS conditions. Results: The results indicate that CPLE had significant increase in the platelet count over the therapy duration, in dengue fever patients, confirming CPLE accelerates the increase in platelet count compared to the control group. There were few adverse events related to GI disturbance like nausea and vomiting which were similar in both groups. This study concluded that Carica papaya leaf extract (CPLE) does significantly increase the platelet count in patients with thrombocytopenia associated with dengue with fewer side effects and good tolerability.

Keywords: Dengue, Caripill, Thrombocytopenia, Platelets.