Abstract

INVITRO ANTI-DIABETIC ACTIVITY OF ETHANOLIC EXTRACT IN ANDROGRAPHIS PANICULATA LEAVES

K. Karthika* and V. Bharathi

Abstract

Plant research has been intensified worldwide in the recent times. A large number of medicinal plants and their purified constituents have immense therapeutic potentials and have been reported to exhibit antidiabetic activity of ethanolic extract Andrographis paniculata. In vitro anti-diabetic was investigated by using alpha amylase, alpha glucosidase, tyrosinase, glucose uptake in yeast cells, heamoglobin glycosylation, extracts on heamoglobin glycosylation, extracts at physiological glucose concentration. The preliminary phytochemical analysis is also carried out. The results of the present study clearly depicted that ethanolic extract of Andrographis paniculata has potent antidiabetic activity.

Keywords: ?-amylase, ?-glucosidase, glucose uptake in yeast cells, glycated heamoglobin, tyrosinase.