Abstract

EVALUATION OF THE INVITRO ANTI CANCER POTENTIAL OF ANOGEISSUS ACUMINATE

*Raghu S., Sankar V., Kothai R. and Arul B.

Abstract

The present study was aimed to investigating the anti cancer activity of the ethanolic extract of Anogeissus acuminate was studied by using different invitro methods Previously the plant has not been investigated for anticancer activity to any greater extent of the plant possessed very good antioxidant properties as evident in the previous studies, it is anticipated that it may possess potential anticancer activity also. The effects of alcoholic extracts of Anogeissus acuminate were tested on HELA i.e., epithelial human cancer cell lines in invitro by Tryphan blue exclusion assay and MTT (3-(4,5-dimethyltiazol-2- yl)-2,5-diphenyl tetrazolium bromide) Assay method. The ethanolic extract of the plant 640μg/ml had shown potent activity in MTT and Tryphan blue exclusion assay. The findings suggest that the ethanol extract of Anogeissus acuminate is a effective anticancer properties, augmenting its therapeutic value.

Keywords: Anogeissus acuminate, Hela, Tryphan blue, MTT, Anticancer.