Abstract

INCORPORATION OF PLACENTA EXTRACT INTO LIPOSOMAL DRUG DELIVERY SYSTEM

Pooja Parmar M.Pharm* and Juhi Dubey PhD

Abstract

Recent Innovations of Liposomal products in Pharmaceutical science for Drug Development, A number of drug candidates which are highly potent and have low therapeutic indication can be targeted to the required diseased site using the liposomal drug delivery system. Drugs encapsulated in liposomes can have a significantly altered pharmacokinetics. The efficacy of the liposomal formulation depends on its ability to deliver the drug molecule to the targeted site over a prolonged period of time, simultaneously reducing its (drug’s) toxic effects. The drugs are encapsulated within the phospholipid bilayers and are expected to diffuse out from the bilayer slowly. The placental extract can be incorporated in the liposomal drug delivery system. The placenta is an organ with the role of protecting and nurturing the baby in a mother’s womb. Naturally, it serves as an interface for the supply of oxygen and nutrients from the mother to the baby, but in order for the baby to grow healthily within the womb, the placenta works in a truly range of ways, including digestion and excretion in place of the internal organs of the still developing baby, the secretion of hormones, and the provision of an immune system to make it difficult for the baby to contract illnesses. On the other hand, the placenta is also an organ that synthesizes “cell growth factor”, a substance that controls the growth and replication of cells. Fetal membrane stem cells are presently preserved mainly for research. However, as these cells gain interest for their regenerative and immunomodulatory properties.

Keywords: Liposome and Phospholipids, Application of Liposome, Placenta Extract and it’s Applications.