Abstract

IN-VITRO THROMBOLYTIC POTENTIAL OF LEAF EXTRACT OF ANOGEISSUS LATIFOLIA

Ruchi C. Bhandakkar* and Vaibhavi N. Garge

Abstract

Thrombotic disorders such as myocardial infarction and cerebral impediment are fatal blood clotting related diseases. The need of safer and reliable herbal medicines for targeted and better drugs is the need of the time, since the thrombosis may further lead to complex blood dyscrasias. Thus the current study is targeted at exploration of the thrombolytic potential of the hydro alcoholic leaf extract of indigenous herb Anogeissus latifolia. The plant has shown presence of phytoconstituents such as tannins, polyphenols which has been reported to show good cardio protective activity. Also, the plant has reported to show antihyperlipidemic activity, good anti-oxidant and anti-atherosclerosis activity. Hence the plant promises to show fair thrombolytic potential. Streptokinase was used as the standard drug for comparison and the saline solution as vehicle control. The plant has shown significant activity compared to both the groups.

Keywords: Thrombolytic potential, Streptokinase, Anogeissus latifolia.