Abstract

RECENT ADVANCES IN THE SYNTHESIS CHROMENES AND ITS DERIVATIVES

Pritesh R. Jain, Samadhan R. Patil and Ashok A. Patil*

Abstract

The chromenes and its derivative are an important class of organic and heterocyclic compounds. The chemistry of these compounds modified day by day because these are one of the most privileged medicinal pharmacophore which appears as an important structural part in many naturally occurring and synthetically prepared compounds. Literature survey reveals that over a last year many chemists and researchers are engaged in the synthesis of chromenes and its various derivatives as they having great biological and pharmacological activities. Generally synthesis of chromenes involve one pot multicomponent reaction of various aldehydes, active methylene compound and enolisable 1,3-dione or derivatives of phenols.

Keywords: Synthesis of chromenes, ionic liquids, nanocatalyst, Michael addition.