Abstract

ANTICANCER AND ANTIMICROBIAL ACTIVITIES OF SINGLE CRYSTALS OF L ALANINE ADDED NICKEL (II) AND COPPER (II) SULPHATES

P. Sagunthala*, V. Veeravazhuthi, P. Yasotha and P. Hemalatha

Abstract

L alanine added nickel sulphate hexa hydrate (LANSH) and L alanine added copper sulphate penta hydrate (LACS) crystals were grown by slow evaporation method in aqueous solution at ambient temperature. The grown crystals were characterized structurally and biologically. Structural details were analysed through single crystal X ray diffraction (SXRD) and FTIR studies. The SXRD study revealed that the crystal LANSH belongs to monoclinic system with space group P2(1)/c. The crystal LACS belongs to triclinic system with space group P1. The grown crystals were tested for their anticarcinogenic effects on cervical cancer cells and antimicrobial behaviour against select bacteria. The results of the tests indicated that these crystals are biologically active. Moreover it is confirmed that the crystal LACS is more efficient than LANSH in both anticancer and antibacterial activities.

Keywords: Inorganic crystals, L alanine, crystal structure, anticancer, antimicrobial.