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Best Article Awards

World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 6-ARYL-4- METHYL-2-THIO-1, 2, 3, 6-TETRAHYDROPYRIMIDINE-5-(N-ARYL) CARBOXAMIDES: A STRUCTURE-REACTIVITY STUDY

S. Manimekalai, K. Radhakrishnan* and S. Chandra Mohan

Abstract

A novel series of Biginelli type dihydropyrimidinones derivatives were synthesized and investigated for their antibacterial activity against Gram positive and Gram negative bacteria. The recorded data of zone of inhibition showed significant broad activity when compared with standard. The structure reactivity correlation of the compounds has been studied.

Keywords: Biginelli type compounds, dihydropyrimidinones derivatives, antibacterial activity, correlation studies.


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